Quinolines and derivatives
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Filtered Search Results
Medchemexpress LLC 8-bromoisoquinoline | 63927-22-0 | 99.5% | C9H6BrN | 10 G
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8-Bromoisoquinoline is a biochemical reagent designed for life science-related research. This organic compound can be utilized as a biological material, for research use only, and is not sold to patients.
- Biochemical reagent for life science research.
- Available in solid and pre-dissolved solution forms.
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Medchemexpress LLC Amino-PEG3-C2-amine | 929-75-9 | MFCD00628164 | 98.0% | 192.26 g/mol | C8H20N2O3 | 10 G
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Amino-PEG3-C2-Amine is a PEG-based linker containing three ethylene glycol units and a terminal primary amine. It functions as a flexible spacer for assembling proteolysis targeting chimera (PROTAC) molecules and other bioconjugates, offering aqueous solubility and a reactive amine handle for downstream coupling and functionalization in synthetic workflows.
- PEG-based spacer with three ethylene glycol units.
- Terminal primary amine for straightforward conjugation.
- Improves solubility and reduces steric hindrance in constructs.
- Molecular weight 192.26 g/mol for predictable stoichiometry.
- Suitable for PROTAC synthesis and other bioconjugation applications.
- Available in multiple laboratory-scale packaging options.
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Medchemexpress LLC 2-Aminoquinoline | 580-22-3 | 144.18 | 5 G
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2-Aminoquinoline (2-Quinolinamine) is a promising compound identified as a bioavailable nNOS inhibitor. While it exhibits low human nNOS inhibition and limited selectivity against human eNOS, it demonstrates antiviral activity against the vaccinia virus and shows potential for research in antineurodegenerative agents.
- Acts as a nNOS inhibitor
- Exhibits antiviral activity against vaccinia virus
- Potential for antineurodegenerative agent research
- Solid appearance
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MOLPORT INC 2 5-DIMETHOXY-N- QUINOLIN- 2UM
NC3232342 2 5-DIMETHOXY-N- QUINOLIN- 2UM
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Medchemexpress LLC 6-Aminoquinoline | 580-15-4 | MFCD00006803 | 144.17 | 25 G
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6-Aminoquinoline is a biochemical reagent used as a biological material or organic compound for life science related research. It is intended for research use only.
- Biochemical reagent for life science research
- Solid appearance, light yellow to brown color
- Purity of 99.79%
- Molecular weight of 144.17
- Store at 4°C, protect from light
- In solvent, store at -80°C for 6 months or -20°C for 1 month (protect from light)
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Medchemexpress LLC 7-bromoquinoline-4-carboxylic acid | 31009-04-8 | MFCD11108751 | 96.1% | 252.06 | C10H6BrNO2 | 1 G
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7-Bromoquinoline-4-carboxylic acid is a brominated quinoline carboxylic acid used as an intermediate in organic synthesis and medicinal chemistry research. It is supplied as a gray to brown solid (C10H6BrNO2; MW 252.06; CAS 31009-04-8) with typical HPLC purity of 96.12%. Storage recommendations: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Used as an intermediate for organic synthesis
- Suitable for medicinal chemistry research applications
- Supplied as a stable solid with defined storage conditions
- Provided with HPLC purity data for quality assessment
- Batch certificate of analysis available for traceability
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Cayman Chemical 8 12isoiPF2aVId11
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An internal standard for the quantification of 8,12-iso-iPF2α-VI by GC- or LC-MS.
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Medchemexpress LLC 5(6)-carboxy-2',7'-dichlorofluorescein diacetate | 127770-45-0 | 97.5% | 529.28 | C25H14Cl2O9 | 10 MG
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5(6)-Carboxy-2',7'-dichlorofluorescein diacetate is a cell-permeant fluorescent tracer used to detect reactive oxygen species (ROS) in live-cell assays. Supplied as the diacetate ester to enable cellular uptake, intracellular esterases cleave the acetate groups to yield the fluorescent carboxy-dichlorofluorescein. It is commonly used in fluorescence-based assays and live-cell imaging.
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eMolecules 873-42-7 | 3,5-dichloropyrazin-2-amine | Combi-Blocks | MFCD11040179 | 163.990 | C4H3Cl2N3 | 98.000 | Nc1ncc(Cl)nc1Cl | 5g | 232333226
3,5-dichloropyrazin-2-amine | Combi-Blocks | 873-42-7 | MFCD11040179 | 163.990 | C4H3Cl2N3 | 98.000 | Nc1ncc(Cl)nc1Cl | 5g | 232333226
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eMolecules 496806-75-8 | 2-Aminoquinoline-5-carboxylic acid | Oakwood Chemicals | MFCD01836227 | 188.186 | C10H8N2O2 | 98.000 | Nc1ccc2c(cccc2n1)C(O)=O | 1g | 480159209
2-Aminoquinoline-5-carboxylic acid | Oakwood Chemicals | 496806-75-8 | MFCD01836227 | 188.186 | C10H8N2O2 | 98.000 | Nc1ccc2c(cccc2n1)C(O)=O | 1g | 480159209
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Medchemexpress LLC TLR7/8 agonist 1 dihydrochloride | 1620278-72-9 | MFCD31657341, MFCD26793840 | 99.7% | 432.39 | C22H27Cl2N5 | 50 MG
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TLR7/8 agonist 1 dihydrochloride is an imidazoquinoline-based small molecule that functions as a dual agonist of Toll-like receptors 7 and 8. Supplied as a dihydrochloride salt in solid form, it is intended for research use in immunostimulation and TLR signaling studies and includes recommended solubility and storage guidance.
- Dual TLR7/TLR8 agonist activity suitable for immunostimulation studies.
- Dihydrochloride salt form improves solubility and handling.
- High purity (99.7%) for reproducible experimental results.
- Solid, off-white to light yellow appearance for easy visual inspection.
- Highly soluble in DMSO; in vitro and in vivo formulation protocols provided.
- Recommended storage: solid at 4°C; in solution -80°C (6 months) or -20°C (1 month).
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Medchemexpress LLC Mal-C6-amine TFA | 731862-92-3 | MFCD11519191 | 99.7% | 310.27 g/mol | C12H17F3N2O4 | 250 MG
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Mal-C6-amine (TFA) is an alkyl chain-based PROTAC linker supplied as the trifluoroacetate salt for use in the synthesis of proteolysis-targeting chimeras. It provides a maleimide-reactive terminus and a six-carbon spacer that enable thiol conjugation and optimized linker length for degrader constructs.
- Maleimide-reactive terminus for selective conjugation to thiols.
- C6 alkyl spacer provides flexibility and appropriate linker length.
- Trifluoroacetate salt form for improved handling and solubility.
- High purity suitable for chemical synthesis (listed as 99.73%).
- Soluble in DMSO for convenient formulation and reactions.
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Medchemexpress LLC Amino-PEG7-amine | 332941-25-0 | MFCD09752883 | 99.3% | C16H36N2O7 | 1 G
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Amino-PEG7-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are designed to selectively degrade target proteins by leveraging the intracellular ubiquitin-proteasome system, utilizing two ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other a specific protein.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates selective protein degradation
- Applicable in cancer targeted therapy
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Medchemexpress LLC 3,6,9,12,15,18,21,24-octaoxapentacosan-1-amine | 869718-81-0 | MFCD13184961 | 98.0% | 383.48 g/mol | C17H37NO8 | 10 G
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m-PEG8-Amine is a monomethyl polyethylene glycol (PEG8) primary amine used as a cleavable linker in antibody-drug conjugate (ADC) synthesis and other bioconjugation applications. It provides an eight-unit PEG spacer with a terminal primary amine for conjugation chemistry, and is supplied at high purity for research use.
- Cleavable PEG8 linker suitable for ADC and bioconjugation chemistry.
- Provides an eight-unit (PEG8) flexible spacer with a terminal primary amine.
- High purity suitable for research use: 98.0%.
- Molecular weight approximately 383.48 g/mol; formula C17H37NO8.
- SMILES COCCOCCOCCOCCOCCOCCOCCOCCN; compatible with common conjugation reactions.
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Medchemexpress LLC STING agonist-8 dihydrochloride | 2745723-90-2 | >98% | C41H48Cl2N14O4 | 25 MG
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STING agonist-8 dihydrochloride, also known as compound 5-AB, is a potent Stimulator of Interferon Genes (STING) agonist with an EC50 of 27 nM in THP1-Dual KI-hSTING-R232 cells. This product is designated exclusively for research purposes, ideal for studying the STING pathway in innate immunity.
- Potent STING agonist.
- Supplied as a dihydrochloride salt, a white to off-white solid.
- Soluble in DMSO at 5 mg/mL (5.74 mM) with sonication and heating.
- Store at -20°C in a sealed container, protected from moisture.
- Useful for immunology, inflammation, and drug discovery research.
- Applied in in vitro and in vivo studies of STING activation.
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